New CRISPR paradigm: HKUST scientists created a DNA-guided Cas12a system that targets RNA, reversing the traditional RNA-guided DNA model. Practical advantages: The DNA guides are more stable, cheaper ...

If you work in a lab, whether you are researching the cutting edge of cell and gene therapy development or running a simple molecular binding screen, the chances are you have done some transfection in ...

Transfection is a crucial non-viral technique for introducing DNA or RNA into cells, yet achieving high efficiency and consistency can be challenging, particularly with difficult cell types.

Transfection techniques are pivotal advances in molecular biology that allow scientists to reliably introduce DNA, RNA, ribonucleoproteins (RNPs), and other molecules into cells. Several delivery ...

A Few Key Considerations Are Essential to Obtain the Best Return from Cell-Based Experiments Because optimal DNA delivery into mammalian cells depends on multiple factors, we recommend optimizing ...

In this interview, News Med talks to Hinnah Campwala about the pivotal role of transfection in modern research and drug discovery. Transfection is a tool that sees widespread use across a diverse ...

Transfection remains a fundamental tool for investigating gene and protein function across diverse systems. Yet variability in constructs, cell types, and delivery methods often complicates ...

A collaboration of scientists at the University of Manchester and the University of Birmingham has explored a more effective and less toxic way of delivering genetic material into cells, a challenge ...

In recent years, there has been an increase in the number of registered clinical trials evaluating recombinant adeno-associated virus (AAV)-based gene therapies, in part due to AAV’s ability to ...