Complementary biochemical and structural findings reveal molecular principles underlying substrate selectivity by a model hyaluronan synthase.

Enzymes are essential for life and are one of the most important types of protein in the human body. Studying enzyme kinetics provides information about the diverse range of reactions in the human ...

Although bioluminescence has been observed for many centuries, its application in biomedicine is relatively recent. Scientists traced back the first reference of bioluminescence to the Greek ...

Chlamydomonas reinhardtii cells disrupted under low pressure in a Yeda press yielded a preparation (``pressate'') with high permeability toward substrates for Class A chloroplasts and intact ...

(A) FPs emit light via chromophore structural transformations and energy transitions. The chromophore forms through autocatalytic cyclization, dehydration, and oxidation of internal amino acids. Upon ...

Chemists at MIT have introduced an engineered biosynthetic enzyme that accepts a wider range of substrates into periwinkle plant culture to make unnatural analogs of alkaloids (Nat. Chem. Biol., DOI: ...

All living things depend on millions of chemical reactions that happen constantly. Chemical reactions that keep you alive happen fast! When you eat food, breathe, play, and grow, all of these are ...

Analysts interested in small volume sample preparation, culture growth, enzyme preservation, enzyme-substrate reactions, DNA amplification, electrophoresis gel degeneration, or serum coagulation ...

Drug discovery is like molecular Tetris. Chemists snap atoms together, adjusting the pieces until everything fits, and suddenly, a molecule makes a promising new medicine. Normally, creating better ...

Adapted from a UC Berkeley news release. Synthetic biologists have successfully engineered microbes to make chemicals cheaply and more sustainably. However, researchers have been limited by the fact ...