Co‑injecting three common amino acids with LNPs dramatically boosted both mRNA delivery and CRISPR gene editing efficiency in preclinical models.

The most common side effects of mRNA vaccines like the COVID-19 shot are well known: soreness, mild fever, and general ...

Researchers at the University of California, Davis and the MRC Laboratory of Molecular Biology in Cambridge, U.K. have solved the the structure of the complex formed when mRNA is being scanned to find ...

The most common side effects of mRNA vaccines like the COVID-19 shot are well known: soreness, mild fever and general malaise. Those symptoms, which ...

Since the COVID-19 pandemic, mRNA vaccines have gained attention as a next-generation pharmaceutical technology. mRNA therapeutics work by delivering genetic instructions that enable cells to produce ...

Genome-wide CRISPR knockout screens to identify cellular regulators of LNP-based mRNA vaccines. mRNAs encoding Green Fluorescent Protein (GFP) were in vitro transcribed (IVT) and delivered to knockout ...

A new class of lipids improve the rates at which lipid nanoparticles (LNPs) successfully deliver RNA therapeutics and gene editing tools, promising to increase their effectiveness of such treatments.

We asked experts about how the technology works, its safety and its potential in medicine. By Nina Agrawal Health Secretary Robert F. Kennedy Jr. has repeatedly questioned the safety of mRNA vaccines ...

Imagine a cancer treatment that precisely targets malignant cells, leaving healthy ones untouched. Consider, also, a cancer treatment that corrects abnormal protein synthesis to produce healthy ...