At a virtual conference in November 2020, the winner of a biennial protein-structure-prediction challenge was announced: AlphaFold. Created by Google DeepMind, this computational tool had blown its ...
With AI, it's now possible for researchers to predict the three-dimensional structures of proteins directly from their ...
When RNA molecules are synthesized by cells — a critical process in the creation of proteins and other cellular functions — they typically undergo a series of “folding” events that determine their ...
RNA molecules are an integral part of the human body: In cells, they ensure the transfer of genetic information and regulate the activity of genes. Some even act as catalysts, allowing chemical ...
Platform combines proprietary AI sequence optimization, novel genetic parts, and lab validation in application-relevant cell models to improve expression and half-life, delivering top candidates in ...
WEST LAFAYETTE, Ind. — Ribonucleic acid, commonly known as RNA, is involved in many biological functions, and some, including gene silencing, are utilitized to cure diseases. RNA has recently gained ...
Example of an RNA thermometer in the gene lpxP, identified in E. coli and conserved across various bacterial species. On the left, the OFF conformation. The Ribosome Binding Site (RBS, green) is ...
LMU researchers have investigated how cationic polymers organize on a molecular level when transporting RNA drugs. Cationic polymers are promising tools for transporting RNA therapeutics or RNA ...
When RNA molecules are synthesized by cells—a critical process in the creation of proteins and other cellular functions—they typically undergo a series of "folding" events that determine their ...