Misshapen proteins cause a mess of trouble—particularly in neurodegenerative diseases. But a new study suggests it's possible ...

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are cut ...

Researchers developed molecules, called splice-switching oligonucleotides (SSOs) that bind to the RNA molecules encoding a protein known as REST. In neuroendocrine tumors, these RNAs are incorrectly ...

Cancers driven by hiccups in RNA processing can’t hide from our immune system, according to new work published today in Cell. A cross-institutional team Fred Hutch Cancer Center and Memorial Sloan ...

Alzheimer's Disease (AD), the leading cause of dementia, affects nearly 40 million individuals globally, resulting in a gradual loss of memory and independence. Despite extensive research over the ...

A single injection into the bloodstream of a mouse corrected a mutation linked to autism in neurons throughout the brain and ...

Bodybuilders and cellular mechanisms agree generating protein is a heavy lift. To complete the task, cells rely on complexes called spliceosomes. These molecular machines snip extra bits out of our ...

Scientists at the Hospital for Sick Children (SickKids) and the University of Las Vegas Nevada (UNLV) have uncovered a genetic link between autism spectrum disorder (ASD) and a rare genetic condition ...

The FDA's decision to grant RMAT status highlights the clinical potential and innovativeness of RZ-001, particularly following the meaningful interim signals from the Phase 1b/2a clinical trial ...

Researchers at The University of Texas MD Anderson Cancer Center and The University of Texas at Austin have identified ...