Scientists have provided unprecedented insight into the presynaptic distribution and profile of mitochondria in the developing and mature calyx of Held. The ability to hear relies on neurons to ...

Researchers from the University of Tokyo reveal how the presynaptic Ube3a E3 ligase, a causal factor in Angelman syndrome, eliminates neural chat. The study helps find a better drug target for the ...

A new study has revealed how tau – a microtubule-binding protein that is implicated in Alzheimer’s disease – weakens transmission across synapses in the brains of mice When injected into presynaptic ...

In the 1950s, advances in microscopy techniques allowed scientists to visualize synaptic communication between two brain cells for the first time. 1,2 However, many details beyond the general synapse ...

General anesthetics have a more widespread effect on the brain than inducing sleep, suggests a new study that could lead to improved drugs for use in surgery. Share on Pinterest Researchers now ...

The discovery of general anesthetics -- compounds which induce unconsciousness, prevent control of movement and block pain -- helped transform dangerous operations into safe surgery. But scientists ...