The most common side effects of mRNA vaccines like the COVID-19 shot are well known: soreness, mild fever, and general ...

Certain lipids discovered in the 1800s presented chemists with structural and functional puzzles that proved unsolvable. And so, the chemists called these lipids sphingolipids, likening them to the ...

Scientists who work with lipid nanoparticles (LNPs) say they have developed a new type of material capable of reaching the lungs and the eyes. They call their study “Thiophene-based lipids for mRNA ...

Alzheimer's disease (AD) is characterised by progressive neurodegeneration and cognitive decline, with emerging evidence implicating disruptions in lipid metabolism as a central element in its ...

Lipid metabolism and storage mechanisms underpin essential cellular processes, ensuring energy homeostasis and membrane integrity. At the cellular level, lipids are synthesised and stored ...

“We’ve never had such an in-depth map of the CD1 lipidome available,” said Patricia Barral, an immunologist at King’s College London who was not involved with the work. “It will enable us to start ...

Researchers are redesigning lipid nanoparticles to do more than shuttle mRNA into cells, with preclinical studies suggesting ...