Modern crop breeding is entering a new era of genome design, led by genome editing technologies as mainstream tools for targeted genome modification. In a review published in Nature Reviews Genetics, ...
The Human Genome Project changed everything. A map of the entire human sequence of DNA was the starting point for an enormous number of discoveries, from disease genes to how humans evolved. But DNA ...
An important DNA modification is methylation, or the addition of a methyl group to the 5th carbon of cytosine. This forms 5-methylcytosine (5mC), typically associated with repression of gene ...
Discover how scientists are harnessing the power of CRISPR to precisely edit DNA, revolutionizing medicine and ethics as they rewrite the very code of life. Pixabay, PublicDomainPictures CRISPR ...
The prime editor is a fusion protein consisting of a catalytically impaired Cas9 nickase (Cas9n) and an engineered reverse transcriptase (RT). The Cas9n is guided by a prime editing guide RNA (pegRNA) ...
This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms at positions 1 and 3, and a primary amine group attached to carbon 4. The two remaining positions ...