I regret to say there is no simple or easy answer to this question. Many people use the word ‘depression’ to refer to normal disappointment or sadness, and there can be little doubt that the concept ...

In a recent study published in Nature Medicine, researchers used functional magnetic resonance imaging (fMRI) data on brain circuit function to derive interpretable, personalized brain circuit ...

Worsened blood circulation from autonomic dysfunction may contribute to depressive symptoms, offering a new avenue for ...

Depression is characterized by a persistent low mood that can affect quality of life. If symptoms usually only occur in the winter months, it may be seasonal affective disorder (SAD), or major ...

“Unspecified depressive disorder” is used when someone displays depressive symptoms, but there isn’t enough information for a specific diagnosis. Depressive symptoms can be complex and may not clearly ...

Some inflammatory markers were associated with depression symptoms in women with diabetes, although the scale used to measure ...

The approval of medicines called second-generation antipsychotics has allowed major depressive disorder (MDD) and other conditions linked to it to be treated. A person with MDD is usually prescribed ...

According to the World Health Organization (WHO), about 332 million people around the world live with depression. Milaneschi is the co-lead author of a new study recently presented at the 2025 ECNP ...

Researchers found that depressed inpatients with high masculine depression scores had a substantially greater acute mental ...

You can still have significant symptoms even if your depression treatment is working. Learn about strategies including ...