DNA phosphorothioate modification is a distinctive epigenetic alteration in which a non‐bridging oxygen atom within the DNA sugar-phosphate backbone is replaced by ...

A UCLA-led study has provided an unprecedented look at how gene regulation evolves during human brain development, showing how the 3D structure of chromatin - DNA and proteins - plays a critical role.

A UCLA-led study has provided an unprecedented look at how gene regulation evolves during human brain development, showing how the 3D structure of chromatin — DNA and proteins — plays a critical role.

N6-Methyladenine (6mA) is emerging as a pivotal epigenetic modification that extends beyond its well‐characterised roles in prokaryotes. In eukaryotic organisms, 6mA has been implicated in the ...

The team of Professor Christof Niehrs at the Institute of Molecular Biology (IMB) in Mainz, Germany, has discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating ...

(Phys.org)—A team of researchers with Massachusetts General Hospital, Harvard Medical School and the Broad Institute has developed a procedure to decode histone modifications that point out gene ...

(The Conversation is an independent and nonprofit source of news, analysis and commentary from academic experts.) Thomas Begley, University at Albany, State University of New York and Marlene Belfort, ...

RNA modifications can encrypt the RNA code and are responsible for a very sophisticated control of RNA function. A Danish-German research team has shown that modified RNA bases have a great impact on ...