Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

To help achieve more precise control of gene therapy, engineers have designed a new control circuit that can keep gene expression levels within a target range. The method could be used to deliver ...

The research field of 'cellular IRESes' lay dormant for decades, as there was no uniform standard of reliable methods for the clear characterization of these starting points for the ribosome-mediated ...

Prolific Machines technology gives developers precise, real-time control over when and how much protein a cell produces.

Gene expression is controlled, in part, by the interactions between genes and regulatory elements located along the genome. Those interactions depend ...

Origin-recognition complex, or ORC, plays an unexpectedly broad role in the regulation of human cell gene expression, according to a study in the journal Cell Reports. This is the first detailed study ...

This voice experience is generated by AI. Learn more. This voice experience is generated by AI. Learn more. Alternative splicing—the way cells edit gene messages—forms a second, independent layer of ...

Platform data establish Modified DNA’s potential to overcome two of the barriers that have kept DNA from becoming a practical ...

Gene expression is controlled, in part, by the interactions between genes and regulatory elements located along the genome.

Gene expression—the way our DNA turns into working molecules—shapes everything from how cells grow to how diseases develop. New research is revealing hidden layers of complexity, from ancient viral ...