The Collaborative Cross (CC) mouse resource has emerged as an indispensable platform for elucidating the genetic basis of complex traits. By combining high levels of genetic diversity from eight ...

David Rand, a professor of natural history at Brown University, explains how studying mitochondria — the cell's energy producers — offers a useful way to understand complex gene-by-gene or ...

For more than a century, Mendelian genetics has shaped how we think about inheritance: one gene, one trait. It is a model that still echoes through textbooks—and one that is increasingly reaching its ...

A growing body of genetic evidence suggests that Neanderthals and Denisovans carried many of the same regulatory gene networks linked to language and vocal anatomy in modern humans, challenging the ...

What makes every person unique? Part of the answer is in our genes. A gene is a basic unit of heredity, the means by which traits get passed from one generation to the next, and genetics is the study ...

Extracting and analyzing relevant medical information from large-scale databases such as biobanks poses considerable challenges. To exploit such "big data," attempts have focused on large sampling ...

“Some genetic diseases are relatively simple, with an essentially one-to-one relationship between the presence of a genetic variant — or a change in a person’s DNA that differs across people — and the ...

In a recent study published in the journal Nature Human Behaviour, researchers from the United States of America conducted a genome-wide association study (GWAS) on personality traits to identify ...

Researchers used genomic structural equation modeling to separate schizophrenia-specific and shared bipolar genetic risks. Schizophrenia-unique variants were linked to lower IQ, while shared variants ...

Genes may play a bigger role in living a longer life, while lifestyle and luck still shape the outcome, according to a new ...