Proceedings of the National Academy of Sciences of the United States of America, Vol. 76, No. 12 (Dec., 1979), pp. 6520-6524 (5 pages) A whole-cell microtechnique for the determination of ...
We present a yeast chemical-genomics approach designed to identify genes that when mutated confer drug resistance, thereby providing insight about the modes of action of compounds. We developed a ...
Vitamin B 12 (cobalamin) is an essential cofactor in several metabolic pathways. Intracellular conversion of cobalamin to its two coenzymes, adenosylcobalamin in mitochondria and methylcobalamin in ...
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