Researchers identify the Munc13-1 protein as a crucial molecular pathway for working memory, linking calcium signaling to synaptic strengthening.

Working memory is a cognitive function that is essential for carrying out everyday activities and temporarily retaining ...

Background: Wnt signaling affects fundamental development pathways by regulating cell proliferation and differentiation. Aberrant activation of Wnt/ß-catenin signaling promotes the development of ...

Northwestern Medicine scientists have discovered how calcium signaling channels in microglia—the primary immune cells of the ...

In one of the cell's key controls of internal calcium levels, channels at the cell membrane open in response to changes in calcium levels in the endoplasmic reticulum (ER). These plasma membrane ...